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Downstream Process Transfer Engineer

Make your mark for patients.

We’re here because we want to build the future and transform patients’ lives for the better.

At UCB, our people are our experiences and achievements, our passion and drive. That’s why we’re looking for talented individuals with diverse backgrounds and experiences - not just the best and brightest, but those who care about making a meaningful difference in the lives of patients. We promote an environment of diversity, openness, and respect where people can make valuable contributions.

An exciting journey lies ahead. Will you join us in pushing the boundaries of what’s possible?

To strengthen our  Biotech Clinical Manufacturing team  in Braine-l’Alleud (Belgium), we are looking for a talented individual to fill the position of:  Downstream Process Transfer Engineer.

As a  Downstream Process Transfer Engineer ,  you are a member of the Global Biologics Manufacturing Sciences & Technology (MSAT) Tech Transfer team and report to the DSP Process Transfer Lead.

You contribute to downstream process tech transfer activities of late-stage and/or commercial biologics to enable launch of these molecules into both internal and external commercial scale facilities.

Key responsibilities are:

  • Supporting Tech Transfer of Downstream Processes (DSP) from Development to Internal Manufacturing and CMOs, and between commercial-scale facilities
  • Supporting the commercial-scale Process Validations for the Downstream Process in Drug Substance manufacturing
  • Providing routine (on-the-floor) support during manufacturing campaigns
  • Providing deviation and investigation support
  • Supporting Continuous Process Verification (CPV) activities
  • Supporting Lifecycle Management (LCM) activities by improving the understanding and robustness of commercial manufacturing processes
  • Supporting Regulatory inspections and filings
  • Acting as a Subject Matter Expert of late-stage and commercial biologics Downstream manufacturing processes
  • Acquiring and maintaining process understanding for late-stage and commercial products
  • More specifically, you will contribute   by:

  • Developing appropriate MSAT procedures and continuously improve upon to ensure rapid, efficient and accurate Process Transfers, LCM, CPV, …
  • Supporting DSP tech transfer and PPQ activities by contributing to process fit-gap assessments, supportive studies, process validation activities, …
  • Authoring technical protocols/reports and ensuring a high scientific and quality standard
  • Performing routine (on-the-floor) support during manufacturing campaigns
  • Providing deviation and investigation support to Manufacturing
  • Supporting CPV and LCM activities, as required
  • Supporting Regulatory inspections and submissions
  • Establishing and maintaining familiarity with contemporary industrial standards, policies, best practices and technologies
  • Interested? For this position you’ll need the following education, experience and skills:

  • Master’s Degree in Life Sciences or equivalent experience, in a relevant scientific discipline
  • Experience in the biopharmaceutical industry is a plus
  • Understanding of Downstream bioprocessing principles (chromatography column steps, ultrafiltration, diafiltration, …)
  • General understanding of biopharma operations and cGMP
  • Ability to communicate effectively and connect with peers from different functions (matrix organization) to ensure projects are delivered
  • Good analytical thinking and problem-solving mindset
  • Familiar with various statistical and data trending techniques
  • Good technical writing skills
  • Ability to manage multiple tasks and meet deadlines with a high tolerance for ambiguity
  • Self-motivated, innovation mindset, can-do attitude, team player
  • Good knowledge of English, both oral and written; knowledge of French is a must.
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    Downstream Process Transfer Engineer

    Company:
    UCB
    City:
    Braine-l'Alleud
    Contract type: 
    Degree level: 
    Master
    Published:
    31.12.2021
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